Annual report pursuant to Section 13 and 15(d)

Stockholders' Equity (Stock Option Activity) (Details)

v3.7.0.1
Stockholders' Equity (Stock Option Activity) (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Number of Shares    
Balance at the beginning of the period (in shares) 465,401 334,686
Options granted (in shares) 1,778,022 321,020
Options forfeited (in shares) (3,416) (176,764)
Options expired (in shares) (398,547) (13,541)
Options exercised (in shares) (5,625)
Balance at the end of the period (in shares) 1,835,835 465,401
Options vested and expected to vest at the end of the period (in shares) 1,829,593  
Options exercisable (in shares) 287,041  
Weighted-Average Exercise Price (Per Share)    
Balance at the beginning of the period (in dollars per share) $ 19.29 $ 34.00
Options granted (in dollars per share) 3.38 3.46
Options forfeited (in dollars per share) 5.86 17.58
Options expired (in dollars per share) 18.38 24.32
Options exercised (in dollars per share) 1.77
Balance at the ending of the period (in dollars per share) 4.15 [1] 19.29
Options vested and expected to vest at the end of the period (in dollars per share) [1] 4.15  
Options exercisable (in dollars per share) [1] 8.35  
Weighted-average fair value of options granted during the period $ 2.41 [1] $ 2.15
Weighted-Average Remaining Contractual Term (in years)    
Balance at the end of the period 9 years 6 months  
Options vested and expected to vest at the end of the period 9 years 6 months  
Options exercisable 8 years 5 months 16 days  
Aggregate Intrinsic Value (in thousands)    
Balance at the end of the period [2] $ 947,896  
Options vested and expected to vest at the end of the period [2] 944,673  
Options exercisable [2] $ 133,792  
[1] The weighted average price per share is determined using exercise price per share for stock options.
[2] The aggregate intrinsic value is calculated as the difference between the exercise price of the option and the fair value of the Company's common stock for in-the-money options at December 31, 2016.